Scientific Publications
SDF-1 Research
Changes in ventricular remodeling and clinical status during the year following a single administration of stromal cell-derived factor-1 non-viral gene therapy in chronic ischaemic heart failure patients: the STOP-HF randomized Phase II trial.
Chung ES, Miller L, Patel AN, Anderson RD, Mendelsohn FO, Traverse J,
Silver KH, Shin J, Ewald G, Farr MJ, Anwaruddin S, Plat F, Fisher SJ,
AuWerter AT, Pastore JM, Aras R, Penn MS
European Heart Journal. 2015 Jun 7.
PMID: 26056125
An open-label dose escalation study to evaluate the safety of administration of nonviral stromal cell-derived factor-1 plasmid to treat symptomatic ischemic heart failure.
Penn MS, Mendelsohn FO, Schaer GL, Sherman W, Farr M, Pastore J, Rouy D, Clemens R, Aras R, Losordo DW.
Circulation Research. 2013 Mar 1;112(5):816-25.
PMID: 23429605
SDF-1 in myocardial repair.
Penn MS, Pastore J, Miller T, Aras R.
Gene Therapy. 2012 Jun;19(6):583-7.
PMID: 22673496
Myocardial CXCR4 Expression Is Required for Mesenchymal Stem Cell Mediated Repair Following Acute Myocardial Infarction.
Feng Dong, MD, PhD; James Harvey, MD; Amanda Finan, BS; Kristal Weber, BS; Udit Agarwal, MD, PhD; Marc S. Penn, MD, PhD
Circulation. 2012; 126: 314-324
PMID: 22685115
Plasmid-based transient human stromal cell-derived factor-1 gene transfer improves cardiac function in chronic heart failure.
Sundararaman S, Miller TJ, Pastore JM, Kiedrowski M, Aras R, Penn MS.
Gene Therapy. 2011 Sep;18(9):867-73.
PMID: 21472007
Continuous delivery of stromal cell-derived factor-1 from alginate scaffolds accelerates wound healing.
Rabbany SY1, Pastore J, Yamamoto M, Miller T, Rafii S, Aras R, Penn M.
Cell Transplant. 2010;19(4):399-408.
PMID: 19995484
Continuous delivery of stromal cell-derived factor-1 from alginate scaffolds accelerates wound healing.
Rabbany SY, Pastore J, Yamamoto M, Miller T, Rafii S, Aras R, Penn M.
Cell Transplant. 2010;19(4):399-408.
PMID: 19995484
Importance of the SDF-1:CXCR4 axis in myocardial repair.
Penn MS.
Circ Res. 2009 May 22;104(10):1133-5.
PMID: 19461103
Role of stem cell homing in myocardial regeneration.
Penn MS, Zhang M, Deglurkar I, Topol EJ.
Int J Cardiol. 2004 Jun;95 Suppl 1:S23-5.
PMID: 15336840
Effect of stromal-cell-derived factor 1 on stem-cell homing and tissue regeneration in ischaemic cardiomyopathy.
Askari AT, Unzek S, Popovic ZB, Goldman CK, Forudi F, Kiedrowski M, Rovner A, Ellis SG, Thomas JD, DiCorleto PE, Topol EJ, Penn MS.
Lancet. 2003 Aug 30;362(9385):697-703.
PMID: 12957092
Poster Presentations